Also known by its brand names Pentasa, Apriso, Asacol, Lialda, Delzicol, 5-ASA or Mesalazine

First medication I was on. Originally prescribed to be taken orally and as an enema. It is an anti inflammatory medication that targets the colon. I had little to no side effects from this medication, but being that it is generally excepted as one of the least potent medications to treat UC, many people start it but eventually switch to something stronger.

Common side effects

  • Muscle and joint pain and stiffness
  • Nausea
  • Heartburn
  • Gas
  • Dry Mouth
  • Itchiness
  • Acne
  • Slight hair loss

Ways its taken

Prescribed as both an oral medication and as an enema you administer yourself at home. The enemas are to get the medication right to the source of the problem, through the most direct route. It is surprisingly easier to do yourself than it sounds actually! Some of the tricks of the trade are making sure you try and get the enema up to body temperature before using it as it will make it more comfortable!
For me the easiest way to actually administer it was by laying on my side, and cocking one knee up to your chest, just like you are getting a scope. When inserting the bottle, try your best to keep it at an angle that points up towards your head. It took me a few tries to learn this makes it SO much easier! I will try and include an image for what I mean, as its tough to explain without a visual aid!


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